Diphtheria and Dogsleds Quiz

1. Which of the following is the most correct way of designating the causative agent for diphtheria?

A. Corynebacterium diptheriae

B. Corynebacterium diphtheria

C. Corynebacterium diphtheriae

D. Corynebacteria diphtheriae

2. Which of the following is NOT a characteristic of the diphtheria organism?

A. non motile

B. Gram negative

C. Gram positive

D. aerobic

3. Metachromatic granules function in:

A. storage

B. attachment

C. motility

D. protein synthesis

4. Who is responsible for discovering metachromatic granules?

A. Roux and Yersin

B. Von Behring and Kitasato

C. Ernest and Babes

D. Klebs and Loeffler

5. The vaccine, known as serum therapy, delivered by dog sled to Nome, Alaska was an example of

A. Passive immunity

B. Active immunity

C. Inactive immunity

D. Innate immunity

6. Passive immunity is defined as

A. Immunity acquired through direct stimulation of the immune system by a foreign substance

B. Specific resistance indirectly by donation of preformed substances

C. Non-specific immunity indirectly acquired from another source

D.

7. Which of the following is an exotoxin made of?

A. protein

B. lipopolysaccharide

C. DNA

D. lipids

8. Which of the following is a characteristic of an exotoxin?

A. Protein

B. Heat stable

C. Non-specific

D. Low potency

9. Which individual is responsible for the development of serum therapy?

A. Emil von Behring

B. Alexandre Yersin

C. Friedrich Loeffler

D. Edwin Klebs

10. The exotoxin for C. diphtheriae acts upon which reaction

A. Protein synthesis

B. Shock

C. Fever

D. Peptidoglycan synthesis

Extra Credit: Which of the following represents the specific mode of action for the diphtheria toxin?

A. Inhibition of nerve impulse

B. Ribosylation of elongation factor 2

C. Binding to mucosal lining

D. shock