Diphtheria Quiz

1. Which of the following is the most correct way of designating the causative agent for diphtheria?

A. Corynebacterium diptheriae

B. Corynebacterium diphtheria

C. Corynebacterium diphtheriae

D. Corynebacteria diphtheriae

2. Which of the following is NOT a characteristic of the diphtheria organism?

A. non motile

B. Gram negative

C. Gram positive

D. aerobic

3. Which of the following represents passive immunity?

A. Injection consisting of toxin - anti-toxin combination.

B. Injection of toxoid prepared by inactivating toxin with formaldehyde.

C. Injection of serum produced in a horse to diphtheria toxin.

D. Exposure to the diphtheria toxin.

4. Which of the following is NOT found in the current vaccine for diphtheria?

A. Inactivated diphtherotoxin

B. Inactivated tetanus toxin

C. Pertussis toxin

D. Endotoxin

5. The exotoxin for C. diphtheriae acts upon which reaction

A. Protein synthesis

B. Shock

C. Fever

D. Peptidoglycan synthesis

6. Which of the following is NOT a characteristic of an exotoxin?

A. Protein

B. Heat stable

C. Non-specific

D. High potency

7. Which of the following represents the specific mode of action for the diphtheria toxin?

A. Inhibition of nerve impulse

B. Ribosylation of elongation factor 2

C. Binding to mucosal lining

D. Metachromatic granules

8. To grow Diphtheria, Loeffler serum agar, Tellurite Agar and Blood agar have been used. How are these agars designated?

A. General Purpose

B. Selective

C. Differential

D. Enriched

9. Which individual was responsible for identifying the organism causing diphtheriae?

A. Edwin Klebs

B. Friedrich Loeffler

C. Emile Roux

D. Emil von Behring

10. Which individual is responsible for the development of serum therapy?

A. Emil von Behring

B. Alexandre Yersin

C. Friedrich Loeffler

D. Edwin Klebs

11. Extra Credit: What must be present in order for the diphtheria exotoxin to be expressed?

A. Presence of ferric ion

B. Presence of a bacterial virus known as bacteriophage

C. Presence of magnesium ions

D. Presence of a cofactor